CR Technology – A feeder-cell based cell culture technology
CR technology (covered under US Patent No. 9,279,106 (issued March 8, 2016), and subsequent patent applications pending in the US and other Jurisdictions) was developed in the laboratory of Dr. Richard Schlegel at Georgetown University. It is a revolutionary new approach to generating unprecedented quantities of biologically important cell types ex vivo. Primary epithelial cells from airway tissues, retina, prostate, breast, intestine, pancreas, hepatocytes, and biliary ductal cells have all proven to be induced to replicate for extended periods under CR conditions. The technology has also been employed successfully to propagate cells from primary tumors, metastatic tumors and patient-derived xenografts.